September 2023

  • Hegde, ML: Fireside chat talk series, Houston Methodist, 19th September 2023.
  • Hegde, ML: “DNA Damage-Repair in Brain Health and Disease: From Mechanisms to Innovative Therapies.” Virtual Lecture at IBRO International Conference, Graneda, Spain, 9-13 September, 2023.

July 2023

  • Hegde, ML: Invited virtual award lecture on “Genomics in Alzheimer’s Disease” at DST SERB workshop on the application of AI/ML in developing early biomarkers for neurological disorders, 3-7 July, 2023, KL University, India
  • Vincent Provasek, graduate student Hegde Lab : Invited to present his novel work on the function of neuronal DNA mismatch repair at the 2023 Gordon Research Conference on Amyotrophic Lateral Sclerosis (ALS) and Related Motor Neuron Diseases in Les Diablerets, Switzerland. He also received a generous travel award from the Texas A&M University Graduate and Professional Student Government to fund his attendance at this prestigious conference

April 2023

March 2023

  • Manohar Kodavati, Joy Mitra, Velmarini Vasquez, Vikas H Malojirao, and Vincent Provasek, attended The Patricia Levy Zusman International Workshop hosted by the Center for Neuroregeneration and Department of Neurosurgery Houston, TX.

November 2022

  • Abstract Presentation: Manohar Kodavati “Abstract title: Mitochondrial DNA damage-repair defects in mutant FUS-linked motor neuron disease and its mitigation via targeted expression of DNA Ligase I”   7th US-EU Conference on Endogenous DNA Damage and Repair, New York.

September 2022

  • Oral Presentation and Travel Award: Vincent Provasek. “RNA/DNA Binding Protein TDP43 Modulates Expression and Post-transcriptional Processing of DNA Mismatch Repair Factors MLH1 and MSH6″ at 13th International Conference on Environmental Mutagens (ICEM) at The Westin Ottawa, Ottawa, Canada.

July 2022

  • Hegde ML.  Chief Guest and Keynote Lecture: International Meet on DNA Damage and Repair in Human Health- Scientific breakthroughs. “A New Era of DNA Repair Mechanisms based Therapeutics for Ageing and Neurological Disorders” at Mangalore University on 25th July -26th 2022.
  • Hegde Lab hosted academic Visitor (Undergrad Student) Leslie Ruiz Lopez (July 2022 -Dec 2022)

June 2022

  • Hegde, ML, Invited Speaker, Autopsy Tissues in Neurodegeneration Research. VA human tissue user group virtual conference.
  • Joy Mitra and Vincent Provasek attended the 2nd Southern Genome Maintenance Conference: June 25-26, 2022, Florida.

April 2022

  • Vincent Provasek received EMGS2022 travel award to present his research in the EMGS annual meeting at Ottawa, Canada to be held during 26-30 August 2022.
  • Hegde, ML, Invited Speaker  International Brain Research Organization (IBRO) workshop on brain health awareness at K L University, India, 07th April 2022. “Title of the talk: A New Era of Genome Damage Response at the Forefront of Brain Health and Therapy”
  • Velmarini Vasquez joined Hegde Lab as Postdoctoral Fellow.

January 2022

  • Hegde ML presented at HMRI Lecture series “DNA Damage-Repair in Brain Health and Disease: From Mechanisms to Innovative Therapies”
  • The Sherman Foundation Parkinson’s Disease Challenge Fund – Hegde; 2022-24.

December 2021

  • Hegde was appointed the Everett E. and Randee K. Bernal Centennial Endowed Director of DNA Repair

November 2021

  • DNA damage and repair deficiency in ALS/FTD-associated neurodegeneration: from molecular mechanisms to therapeutic implication”, by Haibo Wang, Manohar Kodavati, Gavin Britz and Muralidhar L Hegde*, published in “Frontiers in Molecular Neuroscience-Brain Disease Mechanisms”.
  • Jagannatha Rao visited HMRI (Nov 3rd -Nov 5th, 2021)

September 2021

  • Hegde ML. Keynote Speaker, A New Era of Genome Damage Response at the Forefront of Brain Health and Therapy, Vebleo International Webinar for election of Vebleo Fellow, UK.

August 2021

  • Vincent Provasek joined the Hegde lab as MD/Ph.D student

July 2021

  • Hegde ML. Invited Speaker, Potential Neurological Consequences of SARS-COV-2 Involving Genomic Instability and Senescence, Mizoram University, India.

March 2021

  • Hegde ML. Invited Speaker, A New Era of Genome Damage Response Mechanisms at the Forefront of Brain Disorders’ Therapy, University of California, Riverside, USA.
  • Vikas H Malojirao joined Hegde Lab as Postdoctoral fellow

December 2020

  • The Hegde Lab relocated from Smith Tower to the Research Institute Building

November 2020

  • Invited Talk at the 2nd Annual Convention of North East (India) Academy of Science and Technology (NEAST) & International Seminar on Recent Advances in Science and Technology (ISRAST) (16th -18th November 2020) (Virtual) Title: “A New Era of Genome Damage Response at the Forefront of Brain Disorders’ Therapy

September 2020

  • Hegde’s seminar “A New Era of Genome Damage Response at the Forefront of Brain Disorders’ Therapy” at Houston Methodist Research Institute Ernest H. Cockrell Boardroom (R2-311)

June 2020

  • Hegde, ML, Invited Speaker, Autopsy Tissues in Neurodegeneration Research. VA human tissue user group virtual conference, USA

May 2020

  • Hegde ML, Invited Speaker, A new era of targeting DNA repair at the forefront of Brain disorders therapy in the 21st century. Webinar, Mizoram central University, Aizawl, India.

January 2020

  • Hegde ML, Invited Speaker, Natural Compounds and their benefits in Brain health. INDICASAT, City of Knowledge, Panama.
  • Hegde visited INDICASAT, Panama from 29th January to 2nd February along with Houston philanthropist Mr. Rod Cutsinger

December 2019

  • Hegde ML, Plenary Speaker, Genome Repair Deficiency in Brain Disease. 13th ABAP Conference, Vigyan University, Guntur, India.
  • Hegde ML, Invited Speaker, New DNA Damage Response based Therapeutics for Stroke. SV University, Tirupati, India.
  • Hegde received International Senior Scientist Award and Gold Medal, ABAP India

October 2019

  • Velmarini Vasquez completed her Ph.D program

August 2019

  • The Hegde Lab welcomes Manohar Kodavati who joined as a postdoctoral fellow
  • Muralidhar L. Hegde from Methodist Research Institute, USA for ABAP-Senior Scientist Award-2019

July 2019

  • Hegde received NIH Competitiveness Award, Houston Methodist Academic Institute

June 2019

  • Hegde ML, Invited Speaker, DNA damage/Repair deficiency as Biomarker of Neurodegeneration. 7th Mediterranean Neuroscience Meeting, Marrakech, Morocco.

Feb 2019

  • Erika N Guerrero completed her Ph.D program

November 2018

  • Welcome to new member Dr. Dibyendu Banerjee, a visiting scientist to Hegde lab

September 2018

  • Hegde ML, Invited Speaker, Hemin, Iron and Senescence in Intracerebral hemorrhage. 1st Southern Research Conference of genome instability, Mobil, AL, USA.
  • Joy Mitra selected to give an oral presentation at the EMGS Annual Meeting entitled “Missense mutations in TDP-43 and its adverse effects on genome damage repair: Implications in neurodegenerative disorders”.
  • Velmarini Vasquez selected to give a poster presentation at the EMGS Annual Meeting
  • Juan Rodrigo Trujillo selected to give an Oral presentation at EMGS Annual Meeting entitled “TDP-43 as a novel adjuvant target for radioimmunotherapeutic treatment of B16 melanoma”

July 2018

  • Hegde ML, Invited Speaker, TDP-43 and Cancer. Tianjin Medical University Cancer Institute, Tianjin, China.

June 2018

  • Hegde ML, Invited Speaker, Emerging perspectives on genomic instability in motor neuron diseases. INDICASAT, City of Knowledge, Panama.
  • Melo Innovative Scientist Award to Hegde

May 2018

  • Hegde ML, Challenges and Therapeutics of Metal Toxicity in Human Health. Alexandria University, IBRO meeting, Alexandria, Egypt.

March 2018

  • Hegde ML, Brain Diseases and Public Health Awareness. Vijay College, Bengaluru University, Bangalore, India.
  • Hegde ML, TDP-43 and FUS in Neurodegeneration. Indo‐US meeting, Bengaluru, India.
  • Welcome to our new lab member and Research Technician, Priyadarshini Basu

Feb 2018

  • Hegde: Invited Reviewer for Motor Neuron Disease Association, UK (2013; 2018)

January 2018

  • Hegde- Seminar Guest Speaker at the Dept.  Pharmacology & Toxicology, UAMS  “New Mechanism of Genome Repair Inhibition Involving RNA Binding Proteins TDP-43 and FUS in Motor Neuron Disease.”
  • Welcome to our new lab member and postdoctoral fellow, Dr. Girish Talakatta

December 2017

  • Hegde ML, New Mechanisms of TDP-43-genome instability link in motor neuron disease. Indo‐French Conference, IISc, Bangalore, India.

October 2017

  • Welcome to our new lab member, Juan Rodrigo Trujillo

September 2017

  • Hegde ML, RNA binding proteins in Motor Neuron disease. University of Arkansas, Littlerock, CO, USA.
  • Hegde ML, Hegde Lab Update: Neurodegenerative Diseases and Cancer Immunotherapy. Cancer Immunotherapy Group, Houston Methodist, USA

August 2017

  • Hegde ML, Dual role of genome and repair defects in amyotrophic lateral sclerosis. University of North Texas, Fort Worth, TX, USA.

Feb 2017

  • Hegde ML, Metal Toxicity in Neurodegeneration and Stroke. JSS University, Mysore, India.

January 2017

  • Hegde ML, Neurodegenerative Disease: Challenges and Perspectives. University of Texas, San Antonio, TX, USA.

April 2016

  • Hegde ML, Emerging Concepts on genome repair defects in neurodegenerative diseases. UTSA, San Antonio, TX, USA.

Feb 2016

  • Hegde ML, RNA Binding Proteins TDP-43/FUS in DNA Damage Response. Invited Speaker, International Conference on Biomedicine, INDICASAT, City of Knowledge, Panama.

January 2016

  • Invited Guest Editor, Elsevier Book on Genome Repair Defects in Brain Disorders, planned for 2016‐
  • Hegde ML, RNA Binding Proteins TDP-43/FUS in DNA Damage Response. Invited Speaker, Augusta University, Augusta, GA, USA.
  • Hegde ML, RNA Binding Proteins TDP-43/FUS in DNA Damage Response. Invited Speaker, University of Central Florida, Orlando, FL, USA.

Dec 2015

  • International Advisory Board Member (invited), Annual Meeting of Indian Biotechnology Society, Guntur, India (Dec 2015). Invited to organize a mini symposium as co‐chair (5 speakers from USA) on Brain Research
  • Organizer and Co‐Chair, ISN‐ABAP minisymposium on ‘Complexity of Genomics, Oxidative Stress, Neurochemical and Inflammatory Networking in Neurodegenerative disorders and Stroke’, Guntur, India, Dec 2015.
  • Fellow of Association of Biotechnology and Pharmacy (F‐ABAP)
  • International Advisory Board member, Biotechnology Society, India

September 2015

  • Hegde ML, TDP-43 toxicity mediated DNA double strand break repair deficiency in motor neuron disease. Invited Speaker, Department of Neurobiology and Anatomy, West Virginia University, Morgantown, WV, USA
  • Welcome to our new lab member and postdoctoral fellow, Dr. Suganya Rangaswamy

July 2015

  • Hegde received a Career Cornerstone Award in recognition of his recent NIH grant award at the July 2nd, 2015 HMRI Town Hall meeting
  • Erika N Guerrero, graduate student in Hegde laboratory was awarded prestigious travel award from Committee of the Environmental Mutagenesis and Genomics Society (EMGS) to attend the 46th Annual Meeting of the EMGS at the Sheraton New Orleans in New Orleans, Louisiana.

June 2015

  • The Hegde lab welcomes summer students Joey Gu from Brown University and Saher Zaidi from Stony Brook
  • Awarded ISN grant for organizing a symposium as part of annual conference of Association of Biotechnology, Guntur, India, to be held in Dec 2015. Dr. Rao, Director, INDICASAT, Panama and Dr. Hegde will co-chair the symposium. Other speakers are Drs. S. Mitra, I. Boldogh, T. Kent and G. Perry

May 2015

  • Awarded NINDS R01 grant (2015-2020).
  • Welcomed our new lab member and postdoctoral fellow, Dr. Prakash Dharmalingam

April 2015

  • Invited to contribute a chapter for Springer Book on Parkinson’s Disease.
  • Hegde gave an invited talk @ genomic instability group, Baylor College of medicine, Houston.

March 2015

  • Hegde (Speaker) @ ASN Conference, Atlanta, GA.
  • Hegde (Speaker) @ MDA Scientific Conference, Washington, DC.
  • Haibo Wang and Joy Mitra presented posters @ MDA Scientific Conference, Washington, DC.
  • Pavana Dixit attended MDA Conference @ Washington, DC.
  • Invited Guest Editor, Mech Aging Develop, Issue planned for March 2015.

February 2015

  • NIH/NINDS R01 received 4 percentile score. Congratulations to all the lab members and collaborators.

December 2014

  • Hegde attended Cold Spring Harbor Symposium on Neurodegenerative Diseases.

November 2014

  • Hegde (Speaker) @ SFN Conference, Washington, DC
  • Velmarini Vasquez presented poster  @ SFN Conference, Washington, DC. Congratulations Valmarini for the IBRO travel award.
  • Erika Guerrero and Pavana Dixit attended SFN Conference, Washington, DC.

September 2014

  • Hegde (Speaker) @ ALS Association Meeting, Minneapolis, MN.
  • Lab welcomes new graduate student Velmarini Vasquez.

July 2014

  • Awarded Philanthropic Grant from Melo Brain Funds for development of ALS rodent model, A joint venture between Hegde Lab @ HMRI and Dr. K.S. Rao @ INDICASAT, Panama.
  • ALS Association Pilot Research Grant (2014-2016). Congratulations to all the lab members and collaborators.

June 2014

  • Awarded ALS Association Pilot Research Grant (2014-2016). Congratulations to all the lab members and collaborators.

May 2014

  • Hegde (Invited lectures) @ CFTRI, Mysore.
  • Hegde (Invited lectures) @ JSS, Mysore.
  • Hegde (Invited lectures) @ NIMHANS, Bangalore.
  • Hegde (Invited lectures) @ IISc, Bangalore.

May 2014

  • Hegde and Dixit visited Kuvempu University, Shimoga, India.

April 2014

  • Congratulations to Haibo for winning best poster award at Methodist Cancer symposium.
  • Awarded MDA research grant ($2,53,000/3years); May 2014-April 2017

March 2014

  • Awarded NIH competiveness intiative Award from Houston Methodist ($50,000/year)

February 2014

  • NINDS R01 received 28% percentile
  • Lab welcomes new recruits Dr. Joy Mitra and Ms. Erika Guerrero

January 2014

  • MDA grant application received a perfect score of 100 percentile.
  • Lab welcomes new postdoctoral associate Dr. Haibo Wang.

September 2013

  • Hegde was awarded Young Scientist Award by Environmental Mutagenesis and Gentetics Society to attend their annual meeting at Moneterey, CA in Sep, 2013.
  • Hegde joined Houston Methodist Research Institute (HMRI) as Assistant Member (Assistant Professor), his first independent faculty position

July 2013

  • Manuscript accepted in PNAS, Dr. Hegde co-corresponding author

May 2013

  • Hegde presented an oral presentation on Genome Damage Repair deficits in neurodegenerative diseases at the 15th Midwest DNA Repair Symposium in Lexington, KY on May 18-19, 2013.
  • Hegde presented a seminar in the Department of Neuroscience and Cell Biology at UTMB, Galveston.

April 2013

  • Hegde presented a seminar in the Alzheimer’s Association, Houston Chapter.
  • Hegde presented a talk at SBDR meeting, Berkeley, CA

March 2013

  • A publication accepted in JMB

January 2013

  • Hegde presented a seminar in UTSA, san Antonio.
  • Hegde presented a seminar in the Department of Neurology Grand Rounds, UTMB.

December 2012

  • Hegde presented a seminar in Wayne State University, Detroit.

October 2012

  • Hegde received New Investigator Research Grant (NIRG) from Alzheimer’s Association for two years (2012-2014).

September 2012

  • Hegde received a pilot grant from NIEHS Center, UTMB (2012-2013)